USC/Columbia Technology Incubator is a joint incubator created in partnership by the City of Columbia and USC focuses on the creation, development, and recruitment of technology oriented companies with the goal of developing innovative technologies and generating new, high wage jobs.
 
Benedict College Business Development Center was established in 2002 to expand the college's role and effectiveness in addressing the economic and business development needs of small and minority businesses.  The facility hosts a number of business assistance and training programs as well as a small business incubator.